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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FER All Species: 17.58
Human Site: Y578 Identified Species: 35.15
UniProt: P16591 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16591 NP_005237.2 822 94638 Y578 K G N F G E V Y K G T L K D K
Chimpanzee Pan troglodytes XP_517863 822 94653 Y578 K G N F G E V Y K G T L K D K
Rhesus Macaque Macaca mulatta XP_001099988 808 93284 S572 L G E L L G K S Y I H L S A L
Dog Lupus familis XP_851836 820 93016 F574 R G N F G E V F S G R L R A D
Cat Felis silvestris
Mouse Mus musculus P70451 823 94560 Y579 K G N F G E V Y K G T L K D K
Rat Rattus norvegicus P09760 323 37086 Q100 T C K E D L P Q E L K I K F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512215 821 94492 Y577 K G N F G E V Y K G T L K D K
Chicken Gallus gallus P00523 533 59991 E310 S P E A F L Q E A Q V M K K L
Frog Xenopus laevis P13116 532 59718 E309 S P E A F L Q E A Q V M K K L
Zebra Danio Brachydanio rerio XP_693576 842 96630 F587 K G N F G E V F K G T L R D K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P18106 1325 150245 Y1078 R G N F G D V Y K A K L K S T
Honey Bee Apis mellifera XP_623692 782 90822 C545 Y K A Q L K T C K T E V A V K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 95.1 51.4 N.A. 92.9 36.2 N.A. 88.6 24.9 25.1 73.5 N.A. 28 40 N.A. N.A.
Protein Similarity: 100 99.8 96.7 70 N.A. 96.8 37.9 N.A. 95.1 38.6 39.5 85.3 N.A. 43.4 61.3 N.A. N.A.
P-Site Identity: 100 100 13.3 53.3 N.A. 100 6.6 N.A. 100 6.6 6.6 86.6 N.A. 60 13.3 N.A. N.A.
P-Site Similarity: 100 100 13.3 73.3 N.A. 100 20 N.A. 100 13.3 13.3 100 N.A. 73.3 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 17 0 0 0 0 17 9 0 0 9 17 0 % A
% Cys: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 9 0 0 0 0 0 0 0 42 9 % D
% Glu: 0 0 25 9 0 50 0 17 9 0 9 0 0 0 0 % E
% Phe: 0 0 0 59 17 0 0 17 0 0 0 0 0 9 0 % F
% Gly: 0 67 0 0 59 9 0 0 0 50 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 9 0 0 0 % I
% Lys: 42 9 9 0 0 9 9 0 59 0 17 0 67 17 50 % K
% Leu: 9 0 0 9 17 25 0 0 0 9 0 67 0 0 34 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % M
% Asn: 0 0 59 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 17 0 0 0 0 9 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 9 0 0 17 9 0 17 0 0 0 0 0 % Q
% Arg: 17 0 0 0 0 0 0 0 0 0 9 0 17 0 0 % R
% Ser: 17 0 0 0 0 0 0 9 9 0 0 0 9 9 0 % S
% Thr: 9 0 0 0 0 0 9 0 0 9 42 0 0 0 9 % T
% Val: 0 0 0 0 0 0 59 0 0 0 17 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 42 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _